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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LATS1
All Species:
36.06
Human Site:
S978
Identified Species:
56.67
UniProt:
O95835
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95835
NP_004681.1
1130
126870
S978
I
P
P
Q
A
K
L
S
P
E
A
S
D
L
I
Chimpanzee
Pan troglodytes
XP_001173355
1130
126853
S978
I
P
P
Q
A
K
L
S
P
E
A
S
D
L
I
Rhesus Macaque
Macaca mulatta
XP_001090321
809
89257
R673
H
K
M
G
F
I
H
R
D
I
K
P
D
N
I
Dog
Lupus familis
XP_534537
1097
121903
S950
I
P
V
Q
V
K
L
S
P
E
A
R
D
L
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8BYR2
1129
126167
S977
I
P
P
Q
A
K
L
S
P
E
A
S
D
L
I
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506215
1121
123969
T968
I
P
P
Q
A
K
L
T
P
E
A
S
D
L
I
Chicken
Gallus gallus
XP_419666
1136
127431
T984
I
P
P
Q
A
K
L
T
P
E
A
S
D
L
I
Frog
Xenopus laevis
NP_001087838
1118
125984
S964
I
P
A
Q
A
K
L
S
P
E
A
S
D
L
I
Zebra Danio
Brachydanio rerio
NP_001018346
1068
120780
S918
I
P
L
Q
A
K
L
S
P
E
A
T
D
L
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VA38
1105
122470
T969
L
A
N
S
P
L
E
T
Q
Q
K
V
I
N
W
Honey Bee
Apis mellifera
XP_395146
1137
124999
T1000
Y
K
V
I
N
W
E
T
T
L
H
I
P
K
Q
Nematode Worm
Caenorhab. elegans
Q2L6W9
476
55529
V340
I
N
W
Q
Q
T
L
V
F
P
S
D
V
P
I
Sea Urchin
Strong. purpuratus
XP_795100
1199
133231
S1050
I
P
S
Q
A
K
L
S
R
D
A
S
D
F
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53894
756
86927
Y620
S
E
T
P
Q
E
T
Y
R
K
I
M
N
F
E
Red Bread Mold
Neurospora crassa
P38679
598
67999
D462
W
P
P
F
C
A
E
D
S
H
D
T
Y
R
K
Conservation
Percent
Protein Identity:
100
99.6
35.8
50.9
N.A.
92.8
N.A.
N.A.
80.8
85.2
74.7
63.1
N.A.
38.6
40.2
20.7
38
Protein Similarity:
100
99.8
44.7
63.4
N.A.
96.7
N.A.
N.A.
87.1
92.1
83.4
73.7
N.A.
50.2
52.6
29.6
51.9
P-Site Identity:
100
100
13.3
80
N.A.
100
N.A.
N.A.
93.3
93.3
93.3
86.6
N.A.
0
0
26.6
73.3
P-Site Similarity:
100
100
13.3
80
N.A.
100
N.A.
N.A.
100
100
93.3
93.3
N.A.
20
6.6
33.3
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
28
24.4
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
42.3
35.5
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
7
0
54
7
0
0
0
0
60
0
0
0
0
% A
% Cys:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
7
7
7
7
7
67
0
0
% D
% Glu:
0
7
0
0
0
7
20
0
0
54
0
0
0
0
7
% E
% Phe:
0
0
0
7
7
0
0
0
7
0
0
0
0
14
0
% F
% Gly:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
7
0
0
0
0
0
7
0
0
7
7
0
0
0
0
% H
% Ile:
67
0
0
7
0
7
0
0
0
7
7
7
7
0
74
% I
% Lys:
0
14
0
0
0
60
0
0
0
7
14
0
0
7
7
% K
% Leu:
7
0
7
0
0
7
67
0
0
7
0
0
0
54
0
% L
% Met:
0
0
7
0
0
0
0
0
0
0
0
7
0
0
0
% M
% Asn:
0
7
7
0
7
0
0
0
0
0
0
0
7
14
0
% N
% Pro:
0
67
40
7
7
0
0
0
54
7
0
7
7
7
0
% P
% Gln:
0
0
0
67
14
0
0
0
7
7
0
0
0
0
7
% Q
% Arg:
0
0
0
0
0
0
0
7
14
0
0
7
0
7
0
% R
% Ser:
7
0
7
7
0
0
0
47
7
0
7
47
0
0
0
% S
% Thr:
0
0
7
0
0
7
7
27
7
0
0
14
0
0
0
% T
% Val:
0
0
14
0
7
0
0
7
0
0
0
7
7
0
0
% V
% Trp:
7
0
7
0
0
7
0
0
0
0
0
0
0
0
7
% W
% Tyr:
7
0
0
0
0
0
0
7
0
0
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _